Amphiphysin-positive paraneoplastic myelitis and stiff-person syndrome

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Amphiphysin-positive paraneoplastic myelitis and stiff-person syndrome

Finding the underlying etiology of transverse myelitis (TM) can be challenging, as several disorders, including multiple sclerosis (MS), neuromyelitis optica, acute disseminated encephalomyelitis, postvaccine myelitis, Sjögren disease, neurosarcoidosis, infectious myelopathies, or idiopathic TM, may be causative. Paraneoplastic myelopathy, another differential diagnosis, is associated with a br...

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[Stiff-person syndrome and other myelopathies constitute paraneoplastic neurological syndromes].

Stiff-person syndrome (SPS) is an autoimmune neurological disorder characterized by rigidity of the trunk and proximal limb muscles, intermittent superimposed spasms, and increased sensitivity to external stimuli. It has been more than 50 years since Moerch and Woltman reported the first 14 cases with this syndrome. During the last half century, many autoantibodies discovered, such as anti-glut...

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Thymectomy for paraneoplastic stiff-person syndrome associated with invasive thymoma.

2006;132:196-197 J Thorac Cardiovasc Surg Tsukioka and Shigefumi Suehiro Takashi Iwata, Kiyotoshi Inoue, Shinjiro Mizuguchi, Ryuhei Morita, Takuma thymoma Thymectomy for paraneoplastic stiff-person syndrome associated with invasive http://jtcs.ctsnetjournals.org/cgi/content/full/132/1/196 located on the World Wide Web at: The online version of this article, along with updated information and se...

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Stiff leg syndrome and myelitis with anti-amphiphysin antibodies: a common physiopathology?

culty in walking. The symptoms had first appeared 2 weeks earlier. Her medical history included type 2 diabetes treated with metformin and a thyroid goiter treated with surgery and levothyroxine. On clinical examination, she presented permanent hypertonia in the lower limb and bilateral dystonia of the extensor hallucis longus muscles. Intermittent spasms were associated with hypertonia. The sp...

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Stiff Person Syndrome.

Stiff-person syndrome or Moersch-Woltmann is a very rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms involving axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient of stiff person syndrome.

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ژورنال

عنوان ژورنال: Neurology - Neuroimmunology Neuroinflammation

سال: 2016

ISSN: 2332-7812

DOI: 10.1212/nxi.0000000000000285